Reproduction and abundance of the fat sand rat psammomys. Psammomys obesus were cultured by the explant technique 9. Systems medicine exe 1 weizmann institute of science. Islet protection and amelioration of diabetes type 2 in. Toumi a, chlif s, bettaieb j, alaya nb, boukthir a, et al. Rowton1 1division of entomology, walter reed army institute of research, 530 robert grant ave. Seasonal changes in the abundances of parasite and host were monitored in a longitudinal field survey lasting 21 months. Whereas the cortical vasculature is not principally different from that of other species, the medullary vessels show some unique features in the psammomys. Several themes emerged while comparing different species.
This page was last edited on 6 december 2014, at 05. Here, we sought to determine whether a short period of. How can i open pdf files in separate window my pdf. All uploads and downloads are deemed secure and files are permanently deleted from the smallpdf servers within an hour. In class we studied the minimal model for insulin and glucose. Pdf the psammomys obesus lives in natural desert habitat on low energy le diet, however when maintained in laboratory conditions with high energy. Pdf the identification of a tapeworm rodentolepis nana, formerly named hymenolepis. With the help of over 7,000 of the worlds best wildlife filmmakers and photographers, conservationists and scientists, featured multimedia fact files for more than 16,000 endangered species.
Psammomys obesus sand rat, a new animal model of non. All structured data from the file and property namespaces is available under the creative commons cc0 license. Psammomys obesus sand rat is a wellestablished model of type2 diabetes and obesity, which shares most metabolic parameters of the human metabolic syndrome. Explore factors and population characteristics which contribute to different health outcomes that occur in response to climatic change.
The fat sand rat psammomys obesus is the main reservoir host of cutaneous leishmaniasis in north africa and western asia. Wildscreens arkive project was launched in 2003 and grew to become the worlds biggest encyclopaedia of life on earth. Energy requirements of fat sand rats psammomys obesus and their. Role of insulin and the igf system in renal hypertrophy in. Files are available under licenses specified on their description page. Hypoinsulinaemic dm was induced by either administration of streptozotocin or a specially designed diet. Habitat selection by akodon azarae and calomys laucha rodentia, muridae in pampean agroecosystems. Identification of hypothalamic genes implicated in the. What links here related changes upload file special pages permanent link page information wikidata item. Genetic studies in psammomys obesus walder, ken, segal, david, jowett, jeremy, blangero, john, zimmet, paul and collier, greg 2003, genetic studies in psammomys. An psammomys obesus in nahilalakip ha genus nga psammomys, ngan familia nga muridae. Pdf psammomys obesus, a particularly important animal model. The terrarium has a drawer underneath where they can build a tunnel system. Nutritionally induced diabetes in desert rodents as models of type.
Cardiovascular diseases are the most prevalent cause of morbidity and mortality affecting millions of people globally. Characterization of obesity phenotypes in psammomys obesus. Cretzschmar first described psammomys obesus in detail in 1828 from specimens he observed in alexandria, egypt. The vascular organization of the kidney of psammomys obesus. Research article electroretinographic evidence suggesting that the type 2 diabetic retinopathy of the sand rat psammomys obesus is comparable to that of humans ahmed dellaa1,2, maha benlarbi1, imane hammoum1, nouha gammoudi3, mohamed dogui3, riadh messaoud4, rached azaiz5, ridha charfeddine5, moncef khairallah4, pierre lachapelle6, rafika ben chaouachachekir1. The aim of this study was to explore a unique polygenic animal model of metabolic disease as a model of nonalcoholic steatohepatitis by determining the effects of 2% dietary cholesterol supplementation on metabolic and liver endpoints in psammomys obesus israeli sand rat. When they are fed a highenergy he diet, they develop diabetes. Figure 1 shows a frequency histogram for the bodyweightvariable in a total of 633 animals. Electroretinographic evidence suggesting that the type 2. Stages of progression of psammomys obesus to diabetes.
Fall 2003 it is our duty as men and women to proceed as though limits to our. A major impediment to establishing new treatments for nonalcoholic steatohepatitis is the. Psammomys is a genus of rodent in the muridae family. Rapid development of nonalcoholic steatohepatitis in. Daytime activities and social interactions in a colony of the fat sand rats, psammomys obesus, at the negev highlands, israel. Mammal species of the world a taxonomic and geographic reference.
Pdf tapeworm identification in the fat sand rat psammomys. Daytime activities and social interactions in a colony of. The occurrence of increased plasma insulin levels and of hyperglycem. The sand rat psammomys obesus, exhibiting dietinduced metabolic syndrome, might constitute a relevant model. Novel genes in the liver of diabetic psammomys obesus. Before you combine the files into one pdf file, use merge pdf to draganddrop pages to reorder or to delete them as you like. Identification of hypothalamic genes implicated in the development of obesity in psammomys obesus using differential display pcr.
Rearrange individual pages or entire files in the desired order. Foraging habits, hunting and breeding success of lanner falcons falco biarmicus in israel reuven yosef 1 mitrani center for desert ecology, blaustein institute for desert research and department of biology, bengurion university, sede boqer campus, 8d993 israel. Temporal dynamics and impact of climate factors on the. Psammomys species psammomys obesus common name fat sand rat synonyms psammomys algiricus, psammomys roudairei, psammomys tripolitanus, psammomys obesus dianae, psammomys obesus nicolli, psammomys obesus terraesanctae lifespan, ageing, and relevant traits maximum longevity 3. Psammomys obesus, a particularly important animal model for the study of the human diabetic nephropathy. We analyzed phenotypic data including body weight, percentage body fat, blood glucose and plasma insulin concentration for over 600 animals from the psammomys obesus colony at deakin university to investigate the.
I system was studied in normal psammomys obesus gerbils and at 5, 15 and 70 days after the induction of either hyper. The mean body weight for the colony at 16 weeks of age was 198. The x chromosome is the largest of the entire complement, so that it is very easy to identify. On the feeding ecology of psamommys obesus rodentia, gerbillidae in the wadi saoura, algeria pdf. The minimal model steady state solution repeating what we did in class. Overall, this evidence indicated that the delayed timing of sleep during human adolescence is likely to represent a developmental change common across mammalian species table 1. The y chromosome is similar in size to the smallest biarmed autosomes, but. Psammomys obesus is a unique polygenic animal model of obesity and type 2 diabetes. An psammomys obesus in uska species han rodentia nga ginhulagway ni philipp jakob cretzschmar hadton 1828. A hypercaloric high fat diet has been shown to affect cardiac function. Psammomys obesus, a particularly important animal model. There are two entries to the drawer under the two caves. Background and aimsa major impediment to establishing new treatments for nonalcoholic steatohepatitis is the lack of suitable animal models that accurately mimic the biochemical and metabolic characteristics of the disease. To change the order of your pdfs, drag and drop the files as you want.
The psammomys obesus lives in natural desert habitat on low energy le diet, however when maintained in laboratory conditions with high. Various molecular mechanisms have been proposed to underlie glucoseinduced. The sand rat psammomys obesus as an experimental animal in. The aim of this study was to explore a unique polygenic animal model of metabolic disease as a model of nonalcoholic steatohepatitis by determining the effects of.
Psammomys obesus, a particularly important animal model for the study of the human diabetic nephropathy pnina scherzer, 1 shachaf katalan, 1, 2 gay got, 1, 2 galina pizov, 3 irene londono, 4 anca galmoscovici, 1 mordecai m. The gerbil psammomys obesus is a good model to address questions related to the role of insulin resistance and betacell failure in nutritionally induced diabetes. Infection prevalence was positively correlated with vector phlebotomus papatasi density but not with host density. The control aorta was removed and immediately plunged in a petri dish containing dulbeccos modified eagles medium dmem with 10% fetal calf serum fcs supplemented with 1% antibiotics streptomycin 50mgml, penicillin 50 iuml, sigma, 1. The sand rat psammomys obesus is a gerbil species native to deserts of north africa and the middle east, and. Impact of glucotoxicity induced in vivo and in vitro in. The fat sand rat psammomys obesus obesus undergoes agere lated sp ontaneous disc degeneration and is an important model for orthopedic stud ies because c hemonucleolysis or surgical in.
Reproduction and abundance of the fat sand rat psammomys obesus in relation to weather conditions in tunisia volume 248 issue 1 e. Merge pdf files combine pdfs in the order you want with the easiest pdf merger available. Psammomys obesus, a particularly important animal model for the. The sand rat, psammomys obesus, develops type 2 diabetic.
There are two recognised species of psammomys, these being p. To induce hyperinsulinaemic dm, psammomys were raised on a high. If the inline pdf is not rendering correctly, you can download the pdf file here. In this study, superparamagnetic ferrite nanoparticles doped with zinc, exhibiting highly enhanced saturation. Leishmania major infection in the fat sand rat psammomys obesus. This species usually lives in sandy deserts, but may also be found in rocky terrain or saline marsh areas. In order to understand better the transmission of this disease to humans, a longitudinal study of a population of the rodent was carried out in tunisia. The expression levels of key genes involved in hepatic lipid metabolism were measured by real. Supplementary information appendix materials and methods. Data analysis methodology for sand rat model syed raza, marc a. This file is licensed under the creative commons attributionshare alike 4. Psammomys obesus gerbils are particularly prone to develop diabetes and obesity after brief period of abundant food intake. Behavior of psammomys obesus in the algerian sahara 299 along the saoura, oases occur at intervals of several km, and support tamarix trees, cultivated date palms, and small gardens.
Myocardial structural and biological anomalies induced by. The vascular organization of the kidney of psammomys obesus has been studied by injecting silicone rubber into the renal arterial and venous vessels and by standard histological techniques. Psammomys continued on page 2 tamara giles, student, howard. Pdf psammomys obesus, a particularly important animal. The fat sand rat psammomys obesus obesus undergoes agere. Gerbillinae, a diurnal gerbillid rodent, is herbivorous and able to thrive while consuming only the saltbush atriplex. Histological sections of liver from animals on both diets were examined for key features of nonalcoholic steatohepatitis. Fat sand rat psammomys obesus thin sand rat psammomys vexillaris references.
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